drugset / Trial / NCT05979961
Phase III Trial of Concurrent Chemotherapy Alone in Patients With Low-risk Nasopharyngeal Carcinoma
Phase 3
Recruiting
454 enrolled
Sun Yat-sen University
Cancer Hospital of Guizhou Province · collabFirst Affiliated Hospital of Guangxi Medical University · collabGuangzhou Panyu Central Hospital · collabHunan Cancer Hospital · collabTongji Hospital · collabUnion Hospital, Tongji Medical College, Huazhong University of Science and Technology · collabZhongshan People's Hospital, Guangdong, China · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to compare concurrent chemoradiotherapy (CCRT) alone with induction chemotherapy (gemcitabine+cisplatin) plus CCRT in patients with low-risk locoregionally advanced nasopharyngeal carcinoma(NPC).
Timeline
- Start
- 2023-09-07
- Primary completion
- 2026-09
- Completion
- 2029-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Cisplatin | Other / unclassified | 80 mg/m2 | — |
| Comparator | Gemcitabine | Small molecule | 1000 mg/m2 | — |