drugset / Trial / NCT05988008

A Study of CCX168 in Japanese and Caucasian Healthy Adult Males

NCT05988008

Phase 1 Completed 80 enrolled Amgen
RandomizedParallel-groupSingle-blindBasic science

Summary

The objectives of the study will be to investigate the safety and pharmacokinetics of a single oral administration and a twice-daily multiple oral administration of CCX168 in Japanese healthy adult males; and to compare the pharmacokinetics of a single oral administration and a twice-daily multiple oral administration of CCX168 between Japanese and Caucasian healthy adult males.

Timeline

Start
2017-10-23
Primary completion
2018-01-26
Completion
2018-09-20

Drugs

EvaluationDrugModalityDoseRoute
Subject Avacopan Small molecule 10 mg Oral
Subject Avacopan Small molecule 30 mg Oral
Subject Avacopan Small molecule 50 mg Oral
Subject Avacopan Small molecule 100 mg Oral