drugset / Trial / NCT05990751

Multi-modular Chimeric Antigen Receptor Targeting GD2 in Neuroblastoma

NCT05990751 ↗

Phase 1 Active not recruiting 12 enrolled University College, London
NaSingle-groupOpen-labelTreatment

Summary

MAGNETO is a single-centre, non-randomised, open label Phase I clinical trial of an Advanced Therapy Investigational Medicinal Product (ATIMP) in children and teenagers aged 1-16 years with relapsed or refractory neuroblastoma. The study will assess the feasibility of generating the ATIMP (GD2 CAR T cells) and the safety of administering the ATIMP in patients with relapsed or refractory neuroblastoma.

Timeline

Start
2024-04-19
Primary completion
2026-12
Completion
2041-12

Drugs

EvaluationDrugModalityDoseRoute
Subject GD2 CAR T cells Cell therapy — —

Indications