drugset / Trial / NCT05995028

Universal 4SCAR7U Targeting CD7-positive Malignancies

NCT05995028 ↗

Phase 1 Recruiting 30 enrolled Shenzhen Geno-Immune Medical Institute
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this clinical trial is to assess the feasibility, safety and efficacy of universal CAR T cells based on 4SCAR7U design against CD7-positive hematological malignancies using CD7 specific universal CAR T cells. The study also aims to learn more about the function of CD7 targeting CAR T cells and their persistence in patients of hematological malignancies.

Timeline

Start
2023-10-31
Primary completion
2026-09-30
Completion
2026-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject 4SCAR7U Cell therapy — —