drugset / Trial / NCT05995041

Universal CAR-T Cells Targeting AML

NCT05995041 ↗

Phase 1 Recruiting 30 enrolled Shenzhen Geno-Immune Medical Institute
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this clinical trial is to assess the feasibility, safety and efficacy of universal CAR T-cell products targeting CLL-1, CD33, CD38 and CD123 in patients with relapsed and refractory AML. The study also aims to learn more about the function of the universal CAR T cells and their persistency in AML patients.

Timeline

Start
2026-06-01
Primary completion
2029-12-31
Completion
2030-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject CLL-1, CD33, CD38 and/or CD123-specific universal CAR- T cells Cell therapy — Other