drugset / Trial / NCT05995444
A Study to Assess the Effects of Epetraborole on the QT Interval in Healthy Adult Subjects
RandomizedCrossoverQuadruple-blindBasic science
Summary
A single-center, 4-way crossover study to evaluate the effect of single therapeutic and supratherapeutic oral doses of epetraborole on the heart rate (HR) corrected QT interval (QTc) by assessing concentration-QT (C-QT) relationship using exposure-response modeling.
Timeline
- Start
- 2023-06-05
- Primary completion
- 2023-07-26
- Completion
- 2023-08-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Epetraborole | Small molecule | 500 mg | Oral |
| Subject | Epetraborole | Small molecule | 2000 mg | Oral |
| Comparator | Moxifloxacin | Small molecule | 400 mg | — |
Indications
No indication recorded.