drugset / Trial / NCT05996445
A Study of XmAb®662 as Monotherapy or in Combination With Pembrolizumab in Advanced Solid Tumors
Non-randomizedSequentialOpen-labelTreatment
Summary
The purpose of this study is to evaluate the safety, tolerability, and pharmacokinetics of intravenous administration of XmAb662 monotherapy or in combination with pembrolizumab in subjects with advanced solid tumors and to identify the recommended dose regimen that is safe and biologically effective for XmAb662.
Timeline
- Start
- 2023-07-28
- Primary completion
- 2024-05-21
- Completion
- 2024-05-21
Outcome
Outcome not reported
Stopped (Business): “The Sponsor made a business decision to end the study.”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Pembrolizumab | Monoclonal antibody | — | Intravenous |
| Subject | XmAb662 | Unknown | — | Intravenous |