drugset / Trial / NCT06004947

A Study in Healthy Volunteers to Evaluate the Drug-Drug Interaction Potential of CCX168 With Concomitant Medications

NCT06004947

Phase 1 Completed 32 enrolled Amgen
Non-randomizedParallel-groupOpen-labelBasic science

Summary

The primary objective of this study will be to evaluate the drug-drug interaction potential of CCX168 with concomitant medications, as either a perpetrator or a victim, following oral administration of CCX168 to healthy participants.

Timeline

Start
2016-01-14
Primary completion
2016-03-15
Completion
2016-06-10

Drugs

EvaluationDrugModalityDoseRoute
Subject Avacopan Small molecule 30 mg Oral
Subject Celecoxib Other / unclassified 200 mg Oral
Subject Itraconazole Small molecule 200 mg Oral
Subject Midazolam Small molecule 2 mg Oral
Subject Rifampin Small molecule 600 mg Oral