drugset / Trial / NCT06005558
Low Dose Versus High Dose Methylene Blue in Septic Patients
RandomizedParallel-groupDouble-blindTreatment
Summary
The main aim of this study is to examine the various effects of continuous methylene blue infusion in septic cancer patients and to compare it with the traditional infusion of noradrenaline in such patients .
Timeline
- Start
- 2023-08-01
- Primary completion
- 2024-04-29
- Completion
- 2024-05-15
Publications
- Results Chalise SN, Sahib TA, Boyer GA, Pathak V. Methylene Blue in Refractory Shock. Cureus. 2022 Nov 6;14(11):e31158. doi: 10.7759/cureus.31158. eCollection 2022 Nov.
- Shaker EH, Soliman AM, Bedewy AAE, Elrawas MM. Comparative study between high and low dose methylene blue infusion in septic cancer patients: a randomized, blinded, controlled study. BMC Anesthesiol. 2025 Jan 8;25(1):15. doi: 10.1186/s12871-024-02792-3.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Methylene Blue | Diagnostic / imaging agent | 0.25 mg/kg | Intravenous |