drugset / Trial / NCT06010888

Fruquintinib With mFOLFOX6/FOLFIRI as First-Line Therapy for Conversion Surgery in mCRC

NCT06010888

Phase 2 Unknown 92 enrolled Fudan University
NaSingle-groupOpen-labelTreatment

Summary

The goal of this clinical trial is to learn about the efficacy and safety of Fruquintinib with mFOLFOX6/FOLFIRI in patients with mCRC. The main question it aims to answer is: The conversion surgery rate of the therapy mentioned above. The ORR, R0 surgery rate, DCR, PFS, OS, and safety will be evaluated.

Timeline

Start
2023-10-31
Primary completion
2024-10-31
Completion
2026-03-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Fruquintinib Small molecule 4 mg Oral

Indications