drugset / Trial / NCT06020794

The Efficacy of LPPRP in the Treatment of Chondromalacia Patella

NCT06020794

Completed 28 enrolled Kayseri City Hospital
RandomizedParallel-groupSingle-blindTreatment

Summary

Chondromalacia patella(CP) is a common cause of anterior knee pain in the population under 50 years of age. CP is characterized by softening or varying degrees of damage to the patellar cartilage. The positive effects of leukocyte poor-platelet rich plasma (leukocyte poor-platelet rich plasma, LP-PRP) on cartilage repair and degenerative findings are known. However, there is no randomized controlled study on this subject in CP. The aim of this study is to investigate the effect of LP-PRP on pain, function, walking distance and magnetic resonance imaging (MRI) findings in CP patients.The study is the first to investigate the effect of LP-PRP on cartilage measurement with MRI in Chondromalasia Patella. Patients with anterior knee pain who applied to the physical therapy and rehabilitation outpatient clinic of Kayseri City Hospital, patients with Chondromalacia patella in MRI will be included in the study. A total of 40 patients will be randomized into 2 groups. The exercise program will be applied to both groups as a home program for 4 weeks.

Timeline

Start
2021-02-01
Primary completion
2022-08-01
Completion
2022-11-04

Drugs

EvaluationDrugModalityDoseRoute
Comparator Leukocyte-Poor Platelet-Rich Plasma Cell therapy 3 ml Other