drugset / Trial / NCT06024096
Systems Biological Assessment of Statin Effect on Vaccine Responses
RandomizedParallel-groupOpen-labelBasic science
Summary
This study is being done to answer the question: Does the use of statin lipid-lowering medication change the effect of influenza vaccine? The research team will use the knowledge gained from answering this question to understand how this medication affects long-lasting immune responses to vaccines. The researchers will study the immune response to the influenza vaccine in the blood (where antibodies are). The team will also look at how statin therapy affects the bacteria that live in the gut by collecting stool samples. To be in this research, participants must be adults willing to receive vaccines.
Timeline
- Start
- 2023-09-20
- Primary completion
- 2024-12-16
- Completion
- 2024-12-16
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Atorvastatin | Small molecule | 80 mg | — |
| Comparator | Influenza Virus Vaccine | Vaccine | — | — |
Indications
No indication recorded.