drugset / Trial / NCT06024096

Systems Biological Assessment of Statin Effect on Vaccine Responses

NCT06024096

Phase 4 Completed 63 enrolled Emory University
RandomizedParallel-groupOpen-labelBasic science

Summary

This study is being done to answer the question: Does the use of statin lipid-lowering medication change the effect of influenza vaccine? The research team will use the knowledge gained from answering this question to understand how this medication affects long-lasting immune responses to vaccines. The researchers will study the immune response to the influenza vaccine in the blood (where antibodies are). The team will also look at how statin therapy affects the bacteria that live in the gut by collecting stool samples. To be in this research, participants must be adults willing to receive vaccines.

Timeline

Start
2023-09-20
Primary completion
2024-12-16
Completion
2024-12-16

Drugs

EvaluationDrugModalityDoseRoute
Comparator Atorvastatin Small molecule 80 mg
Comparator Influenza Virus Vaccine Vaccine

Indications

No indication recorded.