drugset / Trial / NCT06025084

The Effect of the Egg Shell Nanoparticles Combined With Titanium Dioxide Nanoparticles

NCT06025084

Phase 1 Completed 24 enrolled Egymedicalpedia
RandomizedParallel-groupSingle-blindTreatment

Summary

Dentin hypersensitivity is one of the most commonly occurring clinical dental conditions which is characterized by short and sharp pain which arises from exposed dentin in response to external stimuli, which typically are thermal, evaporative, tactile, osmotic or chemical. Hypersensitive dentin is mostly found in buccal tooth areas, in which enamel is missing because of abrasion, attrition, or erosion. The most generally accepted theory regarding the mechanism of dentin hypersensitivity is the hydrodynamic theory. It proposes that a pain-provoking stimulus increases the flow of the dentinal tubular fluid and consequently, stimulates the nerves around the odontoblasts, leading to dentin hypersensitivity.

Timeline

Start
2022-12-01
Primary completion
2023-03-15
Completion
2023-03-30

Drugs

EvaluationDrugModalityDoseRoute
Comparator Titanium Dioxide Nanoparticles Other / unclassified

Indications