drugset / Trial / NCT06027151

Comparing the Efficacy of Metronidazole and Minocycline Gels for the Treatment of Diabetic Periodontitis Patients

NCT06027151

Completed 380 enrolled Riphah International University
RandomizedParallel-groupSingle-blindTreatment

Summary

This clinical study randomized 380 diabetic chronic periodontitis patients into 4 groups: scaling and root planning alone (group I), scaling and root planning plus metronidazole gel (group II), scaling and root planning plus minocycline gel (group III), and scaling and root planning plus both metronidazole and minocycline gels (group IV). Periodontal measurements including probing depth, gingival color and texture, bleeding on probing, clinical attachment level, and recession were recorded at baseline, 7 days, and 15 days.

Timeline

Start
2022-10-06
Primary completion
2023-07-31
Completion
2023-07-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Metronidazole Small molecule 1 ml Other
Subject Metronidazole Small molecule 1 % Other
Subject Minocycline Small molecule 1 ml Other
Subject Minocycline Small molecule 2 % Other