A Study to Evaluate the Nipocalimab and Certolizumab Combination Therapy in Participants With Active Rheumatoid Arthritis

Summary

The purpose of this study is to evaluate the efficacy of combination therapy with nipocalimab and certolizumab compared to certolizumab monotherapy.

Timeline

Start

2023-08-15

Primary completion

2024-08-29

Completion

2024-10-29

Publications

• Taylor PC, Schett G, Huizinga TWJ, Ibrahim F, Zhou B, Huang S, Gambale J, Wang Q, Liva SG, Leu JH, Hubbard JJ, Leonardo S, Panchakshari RA, Loza MJ, Fei K. Nipocalimab and certolizumab combination therapy in participants with active rheumatoid arthritis despite prior treatment with advanced therapies: results from the phase 2a DAISY-RA study. RMD Open. 2026 Mar 4;12(1):e006464. doi: 10.1136/rmdopen-2025-006464.

Drugs

Indications