drugset / Trial / NCT06029998

Bortezomib in Patients With Metastatic Castration-Resistant Prostate Cancer With PTEN Deletion

NCT06029998 ↗

Phase 2 Active not recruiting 22 enrolled University of Utah
NaSingle-groupOpen-labelTreatment

Summary

The goal of this clinical trial is to test the anti-tumor activity of bortezomib in participants with Metastatic Castration Resistant Prostate Cancer (mCRPC) with PTEN Deletion. The main question\[s\] it aims to answer is if the use of bortezomib will result in a decline in PSA for participants. Participants will receive a sub-cutaneous injection of bortezomib for up 8 cycles. Each cycle is about 21 days.

Timeline

Start
2024-03-11
Primary completion
2026-12
Completion
2028-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Bortezomib Small molecule 1.3 mg/m2 Subcutaneous

Indications