Ceftolozane/Tazobactam Continuous Infusion for Infective Exacerbations of Cystic Fibrosis and Bronchiectasis

Summary

The goal of this clinical trial is to assess the feasibility of ceftolozane/tazobactam (C/T) administered on an outpatient parenteral antibiotic therapy programme to patients with a current infective exacerbation of bronchiectasis or cystic fibrosis related to pseudomonas aeruginosa or burkholderia cepacia spp. organisms. The main question\[s\] it aims to answer are: * Is C/T effective, safe, well-tolerated and able to induce clinical and microbiologic response? * What are mechanisms of antimicrobial resistance are induced by administration of C/T?

Timeline

Start

2023-10

Primary completion

2023-10

Completion

2024-01

Drugs

Indications