drugset / Trial / NCT06041867

Agaricus Bisporus and Influenza Vaccination Response

NCT06041867

RandomizedParallel-groupTriple-blindPrevention

Summary

There are numerous in vitro and animal studies that suggested that mushrooms beneficially influence the immune system. We have recently shown that a wild isolate of the edible Agaricus bisporus mushroom had a clear effect on parameters reflecting a better function of the immune system, both in vitro and in vivo in animals. The question now is whether this efficacy can also be translated to humans. In humans, measuring the antibody response is the golden standard to evaluate immune function. If Agaricus bisporus powder indeed has beneficial effects on the immune system, people with overweight or obesity and higher age might benefit from consuming Agaricus bisporus powder prior to receiving the influenza vaccination.

Timeline

Start
2023-09-14
Primary completion
2023-12-15
Completion
2024-05-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Agaricus bisporus Unknown 5 g
Background Influenza Virus Vaccine Vaccine

Indications

No indication recorded.