drugset / Trial / NCT06041867
Agaricus Bisporus and Influenza Vaccination Response
Completed
88 enrolled
Maastricht University Medical Center
CNC Grondstoffen B.V. · collabScelta Mycofriends B.V. · collab
RandomizedParallel-groupTriple-blindPrevention
Summary
There are numerous in vitro and animal studies that suggested that mushrooms beneficially influence the immune system. We have recently shown that a wild isolate of the edible Agaricus bisporus mushroom had a clear effect on parameters reflecting a better function of the immune system, both in vitro and in vivo in animals. The question now is whether this efficacy can also be translated to humans. In humans, measuring the antibody response is the golden standard to evaluate immune function. If Agaricus bisporus powder indeed has beneficial effects on the immune system, people with overweight or obesity and higher age might benefit from consuming Agaricus bisporus powder prior to receiving the influenza vaccination.
Timeline
- Start
- 2023-09-14
- Primary completion
- 2023-12-15
- Completion
- 2024-05-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Agaricus bisporus | Unknown | 5 g | — |
| Background | Influenza Virus Vaccine | Vaccine | — | — |
Indications
No indication recorded.