drugset / Trial / NCT06045286
High- and Low-dose Radiotherapy Combined With PD-1 Inhibitors for MSS CRLM
NaSingle-groupOpen-labelTreatment
Summary
This pilot phase I trial aims to investigate the efficacy and safety of high- and low-dose radiotherapy combined with programmed cell death-1 (PD-1) inhibitors in microsatellite stable (MSS) metastatic colorectal cancer (mCRC) that have failed second-line immunotherapy or above.
Timeline
- Start
- 2023-09-20
- Primary completion
- 2024-09-30
- Completion
- 2025-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Zimberelimab | Monoclonal antibody | — | — |