drugset / Trial / NCT06056297

A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections

NCT06056297

Phase 3 Recruiting 176 enrolled X4 Pharmaceuticals
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The purpose of this study is to demonstrate the efficacy and evaluate the safety and tolerability of mavorixafor in participants with congenital or acquired primary autoimmune and idiopathic chronic neutropenic disorders who are experiencing recurrent and/or serious infections as assessed by demonstrating its clinical benefit and increasing levels of circulating neutrophils.

Timeline

Start
2024-06-06
Primary completion
2027-09
Completion
2027-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Mavorixafor Small molecule Oral

Indications