drugset / Trial / NCT06056596

Lamivudine and Plasma Markers of Inflammation in Retinal Detachment

NCT06056596

Phase 0 Terminated 2 enrolled University of Wisconsin, Madison
RandomizedParallel-groupSingle-blindTreatment

Summary

The goal of this clinical trial is to test whether an oral medication (lamivudine) enters the eye and reduces blood markers of inflammation in people who undergo retinal detachment surgery (pars plana vitrectomy). Participants will take the study medication or placebo, and the researchers will measure blood markers of inflammation before and after surgery. The researchers will also measure the amount of medication in the blood and fluid inside the participant's eye (which is collected during surgery).

Timeline

Start
2024-01-30
Primary completion
2024-09-06
Completion
2024-09-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Lamivudine Other / unclassified 300 mg Oral