drugset / Trial / NCT06057064

Study Will Assess the Safety, Neutralizing Activity and Efficacy of AZD3152 in Adults With Conditions Increasing Risk of Inadequate Protective Immune Response After Vaccination and Thus Are at High Risk of Developing Severe COVID-19

NCT06057064

Phase 2 Completed 116 enrolled AstraZeneca
RandomizedParallel-groupQuadruple-blindPrevention

Summary

AZD3152, a single mAb, is being developed to have broad neutralizing activity across known SARS-CoV-2 variants of concern for pre-exposure prophylaxis of COVID-19. The aim of the Phase II study is to evaluate the safety, neutralizing activity and efficacy of AZD3152 for pre exposure prophylaxis of COVID-19

Timeline

Start
2023-09-29
Primary completion
2024-05-17
Completion
2024-05-17

Drugs

EvaluationDrugModalityDoseRoute
Subject Sipavibart Monoclonal antibody 300 mg Intramuscular

Indications