drugset / Trial / NCT06061523

A Clinical Trial to Evaluate Bioavailability and Effect of Food for Sotorasib in Healthy Participants

NCT06061523

Phase 1 Withdrawn Amgen
RandomizedCrossoverOpen-labelBasic science

Summary

The primary objectives of the study are to compare the pharmacokinetics (PK) and demonstrate relative bioavailability of sotorasib administered as 4 oral tablets (test) to sotorasib administered as 8 oral tablets (reference) and to assess the effect of food on the PK of sotorasib administered as 4 oral tablets.

Timeline

Start
2024-07-15
Primary completion
2024-09-09
Completion
2024-09-09

Drugs

EvaluationDrugModalityDoseRoute
Subject Sotorasib Small molecule Oral

Indications

No indication recorded.