drugset / Trial / NCT06065657
Effect of Nutritional Ketosis on Alcohol Metabolism
Phase 2/3
Active not recruiting
23 enrolled
University of Pennsylvania
National Institute on Alcohol Abuse and Alcoholism (NIAAA) · collab
RandomizedCrossoverOpen-labelBasic science
Summary
The research study is being conducted in health controls to better understand the effects of ketosis on brain functioning after 3 different, randomly assigned, 3-day dietary interventions and the acute effects of alcohol after consuming about 4-5 alcohol beverages. The labs visits will use magnetic resonance imaging (MRI) scans to study the brain, measuring levels of nicotinamide adenine dinucleotide (NAD), lactate, neurotransmitters glutamate, and Gamma-aminobutyric acid (GABA).
Timeline
- Start
- 2024-02-29
- Primary completion
- 2025-12-01
- Completion
- 2026-12-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Alcohol | Other / unclassified | — | Oral |