drugset
drugset / Trial / NCT06072170

Single Ascending Doses of Kratom in Healthy Nondependent Adults With Opioid Experience

NCT06072170 ↗

Phase 1 Completed 40 enrolled Altasciences Company Inc.
RandomizedSequentialQuadruple-blindBasic science

Summary

Kratom (Mitragyna speciosa) is a plant often used to self-treat conditions such as pain, coughing, diarrhea, anxiety and depression, opioid use disorder, and opioid withdrawal. Due to limited data availability, the goal of this clinical trial is to learn about safety, pharmacokinetics (what the body does to the drug) and pharmacodynamics (what the drug does to the body) of Kratom in adult recreational polydrug users with opioid experience.

Timeline

Start
2023-08-16
Primary completion
2024-01-23
Completion
2024-01-23

Drugs

EvaluationDrugModalityDoseRoute
Subject Kratom Unknown 1 g Oral
Subject Kratom Unknown 3 g Oral
Subject Kratom Unknown 8 g Oral
Subject Kratom Unknown 10 g Oral
Subject Kratom Unknown 12 g Oral

Indications

No indication recorded.