drugset / Trial / NCT06072521
Efficacy of Lactoferrin as an Adjunct Therapy in Patients With Hepatic Encephalopathy
RandomizedParallel-groupOpen-labelSupportive care
Summary
The aim of this study is to evaluate the efficacy of lactoferrin as an adjunct therapy in improving clinical symptoms and laboratory indices in individuals with hepatic encephalopathy.
Timeline
- Start
- 2023-10
- Primary completion
- 2024-09
- Completion
- 2024-10
Publications
- Background Bajaj JS. Hepatic encephalopathy: classification and treatment. J Hepatol. 2018 Apr;68(4):838-839. doi: 10.1016/j.jhep.2017.11.005. No abstract available.
- Background Patidar KR, Bajaj JS. Covert and Overt Hepatic Encephalopathy: Diagnosis and Management. Clin Gastroenterol Hepatol. 2015 Nov;13(12):2048-61. doi: 10.1016/j.cgh.2015.06.039. Epub 2015 Jul 9.
- Background Elsaid MI, Rustgi VK. Epidemiology of Hepatic Encephalopathy. Clin Liver Dis. 2020 May;24(2):157-174. doi: 10.1016/j.cld.2020.01.001. Epub 2020 Mar 2.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Lactoferrin Bovine | Protein / enzyme biologic | 100 mg | — |
| Comparator | Lactoferrin Bovine | Protein / enzyme biologic | 200 mg | — |