drugset / Trial / NCT06074692

PARP Inhibition, Stereotactic Body Radiotherapy and Immunotherapy for Metastatic or Advanced Sarcoma (PRIMA)

NCT06074692

Phase 2 Recruiting 86 enrolled Ruijin Hospital
Non-randomizedParallel-groupSingle-blindTreatment

Summary

The aim of this study is to evaluate the efficacy and safety of PARP Inhibition and programmed cell death protein-1 (PD-1) blockade immunotherapy with concurrent stereotactic body radiotherapy (SBRT) for metastatic or advanced bone and soft tissue sarcoma.

Timeline

Start
2023-06-01
Primary completion
2026-08-30
Completion
2026-12-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Camrelizumab Monoclonal antibody
Subject Fluzoparib Small molecule