drugset / Trial / NCT06077669
Multimodal Brain Imaging of Methylphenidate in Children and Adolescents With ADHD
RandomizedCrossoverQuadruple-blindBasic science
Summary
The goal of this proposal is to develop brain imaging tools to measure the effects of methylphenidate in children and adolescents with attention deficit hyperactivity disorder (ADHD). Methylphenidate is an FDA-approved treatment for ADHD. Specifically, the investigators will correlate brain activity during cognitive tasks and brain chemistry with cognitive performance. These measures could help the investigators understand how current ADHD medications work and then could be used to develop novel drugs to treat ADHD in children and adolescents.
Timeline
- Start
- 2024-04-16
- Primary completion
- 2028-12
- Completion
- 2029-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Methylphenidate | Small molecule | 5 mg | Oral |
| Subject | Methylphenidate | Small molecule | 10 mg | Oral |