drugset / Trial / NCT06077669

Multimodal Brain Imaging of Methylphenidate in Children and Adolescents With ADHD

NCT06077669

Phase 4 Withdrawn Johns Hopkins University
RandomizedCrossoverQuadruple-blindBasic science

Summary

The goal of this proposal is to develop brain imaging tools to measure the effects of methylphenidate in children and adolescents with attention deficit hyperactivity disorder (ADHD). Methylphenidate is an FDA-approved treatment for ADHD. Specifically, the investigators will correlate brain activity during cognitive tasks and brain chemistry with cognitive performance. These measures could help the investigators understand how current ADHD medications work and then could be used to develop novel drugs to treat ADHD in children and adolescents.

Timeline

Start
2024-04-16
Primary completion
2028-12
Completion
2029-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Methylphenidate Small molecule 5 mg Oral
Subject Methylphenidate Small molecule 10 mg Oral