drugset / Trial / NCT06081894

Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Placebo in Adults With Symptomatic nHCM

NCT06081894

Phase 3 Active not recruiting 500 enrolled Cytokinetics Bayer · collabSanofi · collab
RandomizedParallel-groupDouble-blindTreatment

Summary

This clinical trial will study the effects of aficamten (versus placebo) on the quality of life, exercise capacity, and clinical outcomes of patients with non-obstructive hypertrophic cardiomyopathy.

Timeline

Start
2023-08-30
Primary completion
2026-06
Completion
2026-09

Drugs

EvaluationDrugModalityDoseRoute
Subject Aficamten Small molecule 5 mg Oral
Subject Aficamten Small molecule 10 mg Oral
Subject Aficamten Small molecule 15 mg Oral
Subject Aficamten Small molecule 20 mg Oral