drugset / Trial / NCT06084637

Comparison Between Intra-articular Infiltrations of PRP, MFAT, and PRP-MFAT in the Treatment of Symptomatic Knee Osteoarthritis.

NCT06084637

Phase 3 Not yet recruiting 180 enrolled Assistance Publique Hopitaux De Marseille
RandomizedParallel-groupSingle-blindTreatment

Summary

This research protocol evaluate the efficacity of intra-articular injections of autologous microfat associated with a preparation of autologous PRP, in symptomatic, resistant to first-line medical treatment, degenerative or post-traumatic cartilage lesions of the knee. The primary objective of this study is to show the superiority of intra-articular injection of autologous microfat combined with autologous PRP preparation compared to injection of microfat or PRP used alone, on the KOOS score at 6 months.

Timeline

Start
2024-02-02
Primary completion
2027-02-01
Completion
2028-03-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Platelet Rich Plasma Other / unclassified 5 ml Other
Subject microfat Other / unclassified 5 ml Other

Indications