drugset / Trial / NCT06085079
Ixekizumab for the Management of Refractory Non-Infectious Uveitis: A Proof-of-Concept Study
Phase 4
Unknown
20 enrolled
Massachusetts Eye Research and Surgery Institution
Eli Lilly and Company · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
The objective of this study is to explore the efficacy of ixekizumab in treating patients with a diagnosis of non-infectious intermediate, posterior, panuveitis, or chronic steroid-dependent anterior uveitis who had failed treatment with a classic synthetic DMARD including methotrexate, mycophenolate, cyclosporin, azathioprine, cyclophosphamide and/or at least one anti-TNF agent including adalimumab, infliximab, etanercept, golimumab or certolizumab.
Timeline
- Start
- 2022-06-01
- Primary completion
- 2024-12-30
- Completion
- 2024-12-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ixekizumab | Monoclonal antibody | 80 mg | Subcutaneous |