drugset / Trial / NCT06099379

Modulation of THC Effects by CBD: a Dose-ranging Study

NCT06099379

Phase 1/2 Recruiting 100 enrolled University of Montreal Hospital Centre (CHUM)
RandomizedCrossoverQuadruple-blindOther

Summary

The purposes of this study are 1) to determine if CBD modulates THC-induced acute psychoactive effects at different CBD:THC ratios, compared with the control product (0:20, 20:20, 40:20, 80:20, 120:20) and 2) to determine if different doses of CBD modulate other THC induced behavioral effects, compared with the control product and 3)To explore qualitatively whether CBD modulates THC effects by mechanisms that are not detected with standard clinical research tools.

Timeline

Start
2024-06-27
Primary completion
2026-07-31
Completion
2026-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Cannabidiol Other / unclassified 0 mg Inhaled
Subject Cannabidiol Other / unclassified 20 mg Inhaled
Subject Cannabidiol Other / unclassified 40 mg Inhaled
Subject Cannabidiol Other / unclassified 80 mg Inhaled
Subject Cannabidiol Other / unclassified 120 mg Inhaled