drugset / Trial / NCT06106412

Efficacy of Oocyte Activation With Two Types of Ca2+ Ionophore.

NCT06106412

RandomizedParallel-groupOpen-labelTreatment

Summary

This study is a prospective ranzomized analysis including 372 human oocytes from 44 women. Half of the oocytes from the same patient will be randomly allocated to induce oocyte activation using two protocols: in protocol nº 1 we will use ionomycin (prepared solution), protocol nª2 A23187 (GM508 CultActive Gynemed) will be applied. Non treated oocytes will serve as control. Oocyte fertilization rates, embryo development and embryo quality will be analyzed. Obstetrics variables of offspring will be also followed and compared.

Timeline

Start
2024-01-01
Primary completion
2024-12
Completion
2024-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Ionomycin Small molecule
Comparator calcimycin Small molecule

Indications