drugset / Trial / NCT06113289

A Phase 1B/2A Trial of Combination of ASTX727 With ASTX029 in Acute Myeloid Leukemia

NCT06113289

Phase 1/2 Withdrawn M.D. Anderson Cancer Center
RandomizedSingle-groupOpen-labelTreatment

Summary

To find the recommended dose of the study drugs ASTX727 and ASTX029 that can be given to patients with relapsed/refractory AML. The goal of Part 2 of the study is to learn if the dose of study drugs found in Part 1B can help to control AML.

Timeline

Start
2024-02-08
Primary completion
2025-03-06
Completion
2025-03-06

Drugs

EvaluationDrugModalityDoseRoute
Subject ASTX029-01 Unknown Oral
Subject ASTX727 Unknown Oral