drugset / Trial / NCT06119880

The Effect of PERT on Patients Undergoing Pancreaticoduodenectomy

NCT06119880

Phase 4 Unknown 100 enrolled Ruijin Hospital
RandomizedParallel-groupSingle-blindTreatment

Summary

A comprehensive perioperative nutrition management plan for pancreaticoduodenectomy, primarily based on pancreatic enzyme replacement therapy (PERT). A prospective randomized controlled study was conducted to comprehensively analyze the perioperative nutritional status of patients undergoing pancreaticoduodenectomy, with the aim of exploring: 1. The effect of PERT on postoperative complications and physiological status after pancreaticoduodenectomy; 2. The efficacy of PERT treatment on clinical symptoms, nutritional indicators, and quality of life (QOL) related to pancreatic exocrine dysfunction (PEI) after pancreaticoduodenectomy; 3. The personalized full process nutrition management strategies based on risk factor stratification.

Timeline

Start
2023-11-01
Primary completion
2024-12-31
Completion
2025-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Shouhui Tongbian Capsules Traditional medicine (herbal / TCM) 40000 iu
Subject Shouhui Tongbian Capsules Traditional medicine (herbal / TCM) 50000 iu