Assessment of Coated Orthodontic Miniscrews With Chlorhexidine Hexametaphosphate Antimicrobial Nanoparticles

NCT06124235 ↗

Phase 3 Completed 39 enrolled University of Baghdad

RandomizedParallel-groupOpen-labelPrevention

Summary

Aim To compare between orthodontic miniscrews coated and uncoated with CHX- HMP NP nanoparticles.

Timeline

Start: 2023-02-10
Primary completion: 2023-11-12
Completion: 2023-12-20

Outcome

Missed primary endpoint

paper success rates of the miniscrews for coated and uncoated samples were 81.3% and 84.4%, respectively, which was a statistically insignificant difference. PMID 39521698 ↗

Publications

Al-Hilaly AA, Alhuwaizi AF. Assessment of coated orthodontic miniscrews with chlorhexidine hexametaphosphate antimicrobial nanoparticles: A randomized clinical trial. J World Fed Orthod. 2025 Apr;14(2):67-75. doi: 10.1016/j.ejwf.2024.09.006. Epub 2024 Nov 8.

Drugs