drugset / Trial / NCT06132503

Safety, Pharmacokinetics, and Clinical Activity of LP-284 in Adult Patients With Relapsed or Refractory Lymphomas and Solid Tumors

NCT06132503 ↗

Phase 1 Recruiting 110 enrolled Lantern Pharma Inc.
NaSingle-groupOpen-labelTreatment

Summary

The goal of this clinical trial is to evaluate the safety and tolerability of escalating doses of LP-284 and to determine the maximum tolerated dose (MTD) and the recommended Phase 2 dose (RP2D) in patients with relapsed or refractory (R/R) lymphomas and solid tumors. The secondary objectives are to characterize the pharmacokinetics (PK) of LP-284 and to assess clinical activity of LP-284.

Timeline

Start
2023-01-03
Primary completion
2028-11-30
Completion
2028-11-30

Drugs

EvaluationDrugModalityDoseRoute
Subject LP-284 Small molecule — Intravenous

Indications