Cognitive Dysfunction and Inflammation in Depression: Experimental Inhibition Via Infliximab

Summary

This study is a mechanistic randomized controlled trial that investigates whether inhibition of tumor necrosis factor signaling via intravenous infusion of infliximab improves psychomotor speed and executive functioning in depressed individuals who exhibit an inflammatory phenotype.

Timeline

Start

2025-01-23

Primary completion

2028-08-31

Completion

2029-01-31

Drugs

Indications