drugset / Trial / NCT06140745

Evaluation of Dentifrice Formulations to Remineralize Enamel and Dentine Subsurface Lesions in a Double-Blind In-Situ Clinical Trial

NCT06140745

Completed 10 enrolled Procter and Gamble
RandomizedCrossoverTriple-blindTreatment

Summary

To compare the remineralization and demineralization inhibition potential of early subsurface carious lesions in enamel in situ after rinsing with five different aqueous slurries of toothpaste formulations. Percent remineralization (%R), i.e. the % change in ΔZ values relative to ΔZd, will be the primary outcome measure.

Timeline

Start
2020-10-05
Primary completion
2021-02-21
Completion
2021-02-21

Drugs

EvaluationDrugModalityDoseRoute
Comparator NaF Unknown 1100 ppm
Comparator NaMFP Unknown 1500 ppm

Indications