drugset / Trial / NCT06140745
Evaluation of Dentifrice Formulations to Remineralize Enamel and Dentine Subsurface Lesions in a Double-Blind In-Situ Clinical Trial
RandomizedCrossoverTriple-blindTreatment
Summary
To compare the remineralization and demineralization inhibition potential of early subsurface carious lesions in enamel in situ after rinsing with five different aqueous slurries of toothpaste formulations. Percent remineralization (%R), i.e. the % change in ΔZ values relative to ΔZd, will be the primary outcome measure.
Timeline
- Start
- 2020-10-05
- Primary completion
- 2021-02-21
- Completion
- 2021-02-21
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | NaF | Unknown | 1100 ppm | — |
| Comparator | NaMFP | Unknown | 1500 ppm | — |