drugset / Trial / NCT06145438
Comparing the Safety and Efficacy in the Use of Hormonal Therapy on Endometriosis Patients After Conservative Surgery
RandomizedParallel-groupOpen-labelTreatment
Summary
The goal of this clinical trial is to compare safety and efficacy in endometriosis patient after conservative surgery. The main question\[s\] it aims to answer are: 1. Health-related quality of life (HRQoL) 2. VAS score 3. Beta estradiol 4. TNF Alpha 5. Adnexal mass recurrence Participants will be randomized into 4 groups, each group will receive: 1. Leuprolide Acetate injection/month 2. Dienogest 2 mg/day 3. COC (mycrogynon)/day 4. DMPA injection 150mg/month Researcher will compare the efficacy and safety in the assigned group.
Timeline
- Start
- 2023-09-04
- Primary completion
- 2024-08-19
- Completion
- 2024-11-19
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dienogest | Small molecule | 2 mg | Oral |
| Comparator | Leuprolide | Other / unclassified | 3.75 mg | Intramuscular |
| Subject | etinilestradiol | Unknown | 30 ug | Oral |
| Subject | levonogestrel | Unknown | 150 ug | Oral |
| Subject | medroxyprogesterone acetate | Other / unclassified | 150 mg | Intramuscular |