drugset / Trial / NCT06145945

Effect of Intraperitoneal Ropivacaine on Visceral Pain After Laparoscopic Gastrectomy

NCT06145945 ↗

Unknown 72 enrolled SanQing Jin
RandomizedParallel-groupTriple-blindTreatment

Summary

Visceral pain is obvious and lasts for a long time in patients after laparoscopic gastrectomy.Relieving the visceral pain is of great significance for patients' postoperative emotional experience, functional recovery and reducing the formation of long-term chronic pain. However, there is no clear clinical consensus on relieving visceral pain by now, so effective clinical methods to relieve visceral pain need to be explored urgently. Intraperitoneal spraying local anesthetics is a simple and inexpensive method, which has been proved to be safe and effective in randomized controlled trials and Meta-analysis of various types of surgery.However, its effect in clinical research is still controversial and many studies lack evaluation of postoperative recovery quality, so it has not been widely used in clinical practice. This study aims to explore the effect of intraperitoneal spraying ropivacaine (long-acting amide local anesthetic) on visceral pain after laparoscopic gastrectomy, and to systematically evaluate its effect on the recovery of gastrointestinal function and the inflammatory factors (IL-6, TNF-α) in abdominal drainage fluid.

Timeline

Start
2023-11-25
Primary completion
2024-03-03
Completion
2024-07-07

Publications

Drugs

EvaluationDrugModalityDoseRoute
Subject Ropivacaine Other / unclassified 0.5 % Other
Subject Ropivacaine Other / unclassified 20 ml Other

Indications

No indication recorded.