drugset / Trial / NCT06146777

Multi-classifier System for Stratifying Stage III Papillary Renal Cell Carcinoma of Receiving Adjuvant Therapy

NCT06146777 ↗

Phase 3 Not yet recruiting 468 enrolled First Affiliated Hospital, Sun Yat-Sen University
RandomizedParallel-groupOpen-labelTreatment

Summary

The goal of this trial is to test whether patients with stage III papillary renal cell carcinoma (pRCC) could benefit from adjuvant therapy or not. The investigators invented a multi-classifier system that was successfully categorise patients with stage III pRCC into high-risk and low-risk groups. Here the investigators randomly assign classifier-defined high risk patients of stage III pRCC into adjuvant pembrolizumab group placebo group. Disease-free survival and overall survival are the end points of observation.

Timeline

Start
2023-12-01
Primary completion
2030-12-01
Completion
2030-12-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Pembrolizumab Monoclonal antibody 200 mg Intravenous