Safety and Preliminary Efficacy of BNT314 in Cancer Patients With Malignant Solid Tumors

Summary

The purpose of this first-in-human study is to find out if BNT314 is safe when it is used alone in patients with different types of cancer. This is a dose escalation study in which patients will be assigned to multiple dose levels (DLs) of BNT314 given alone. By escalating the dose with a small group of patients, the Maximum Tolerated Dose which is the highest dose with acceptable safety and manageable side effects, or the maximum administered dose will be investigated.

Timeline

Start

2023-11-30

Primary completion

2027-06

Completion

2028-03

Drugs

Indications