A Study Assessing the Effects of an Experimental Dentifrice in Maintaining Tooth Color Following Tooth Bleaching

Summary

The main aim of this study is to investigate the ability of an experimental dentifrice containing 5 percent (%) potassium nitrate (KNO3), 1% alumina and 5% sodium tripolyphosphate (STP), to maintain tooth color and reduce extrinsic dental stain accumulation following peroxide tooth bleaching compared to a regular fluoride dentifrice.

Timeline

Start

2023-11-27

Primary completion

2024-07-18

Completion

2024-07-18

Outcome

Missed primary endpoint

registry analysis (superiority test); Test Dentifrice vs Reference Dentifrice; p = 0.9141; Adjusted Mean Difference -0.05 (95% CI -1.04 to 0.93); ANOVA NCT06150573 ↗

Drugs

Indications