drugset / Trial / NCT06150859

Ayahuasca Assisted Psychotherapy for Grief

NCT06150859

Phase 2 Unknown 84 enrolled Beckley Med Foundation
Non-randomizedParallel-groupOpen-labelPrevention

Summary

The aim of this study is to compare the effectiveness of an ayahuasca-assisted constructivist therapy with constructivist therapy and no treatment to decrease the severity of grief. A secondary purpose is to assess the effectiveness to prevent Persistent Complex Bereavement Disorder and Prolonged Grief Disorder, and to assess potential changes in avoidance, meaning-making and self-clarity. Subjective effects and Acceptance promoting effects of psychedelic drug are assessed after ayahuasca administration. A non-randomized controlled trial is proposed with three arms involving an experimental group (ayahuasca in concert with psychotherapy) and two control groups (psychotherapy and no treatment) with pretest, posttest and 3 months follow-up.

Timeline

Start
2021-10-15
Primary completion
2024-04-15
Completion
2024-06-15

Drugs

EvaluationDrugModalityDoseRoute
Subject Ayahuasca Traditional medicine (herbal / TCM) 0.75 mg/kg

Indications

No indication recorded.