The Role of Histamine in Muscle Protein Synthesis Following Resistance Training

Recruiting 50 enrolled University Ghent Research Foundation Flanders · collab

RandomizedParallel-groupTriple-blindBasic science

Summary

Blocking histamine H1/H2 receptors blunts chronic endurance training adaptations. The current study addresses the following research question: "What is the influence of histamine H1 signaling on training adaptations following ten weeks of resistance training in human skeletal muscle." Results from this study will yield more insights into the molecular mechanisms of adaptations to exercise training.

Timeline

Start: 2023-09-01
Primary completion: 2026-12-31
Completion: 2026-12-31

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Fexofenadine	Unknown	180 mg	Oral

Indications

No indication recorded.