drugset / Trial / NCT06154226
Prevention of Post-Cardiac Surgery Acute Kidney Injury by Proton Pump Inhibitor
Phase 2
Completed
100 enrolled
The University of Texas Health Science Center, Houston
Society of Cardiovascular Anesthesiologists · collab
RandomizedParallel-groupSingle-blindPrevention
Summary
The purpose of this study is to determine whether perioperative intravenous administration of pantoprazole will improve kidney function parameters following cardiac surgery with cardiopulmonary bypass compared to famotidine and to determine whether perioperative intravenous administration of pantoprazole will decrease the incidence of postoperative Acte Kidney Injury (AKI) and major adverse kidney events (MAKE).
Timeline
- Start
- 2024-01-10
- Primary completion
- 2024-09-17
- Completion
- 2024-10-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Famotidine | Other / unclassified | 20 mg | Intravenous |
| Subject | Pantoprazole | Other / unclassified | 40 mg | Intravenous |