drugset / Trial / NCT06159478

Binimetinib in Patients With BRAF Fusion-positive Low-grade Glioma or Pancreatic Cancer (Perfume)

NCT06159478

NaSingle-groupOpen-labelTreatment

Summary

This study is an open-label, parallel, 2-cohort, multicenter, investigator-initiated Phase 2 trial to evaluate the efficacy and safety of binimetinib in patients with advanced or recurrent low-grade glioma or pancreatic cancer harboring BRAF fusion/rearrangement.

Timeline

Start
2023-03-29
Primary completion
2027-02-28
Completion
2027-09-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Binimetinib Small molecule 45 mg Oral