drugset
drugset / Trial / NCT06167057

POST URS Chemotherapy Instillation

NCT06167057 ↗

Recruiting 264 enrolled Carmel Medical Center
RandomizedParallel-groupSingle-blindTreatment

Summary

The goal of this study is to evaluate the safety and oncological outcomes of single chemotherapy bladder instillation following endoscopic treatment for UTUC in UTUC suspected patients .The main aim is to determine the efficacy of a single, post URS, chemotherapy bladder instillation to reduce IVR. Participants will be given single chemotherapy bladder instillation within 24h following ureteroscopy and will follow routine follow-up for IVR which will include white light cystoscopy ;patients with suspected IVR (based on either imaging or cystoscopy) will undergo TURBT.

Timeline

Start
2023-04-17
Primary completion
2028-01-30
Completion
2028-01-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Gemcitabine Small molecule 2 g Other
Subject Mitomycin C Other / unclassified 40 mg Other

Indications

No indication recorded.