drugset / Trial / NCT06184321

Alteplase Through an Indwelling Pleural Catheter for the Management of Symptomatic Septated Malignant Pleural Effusion

NCT06184321

Phase 0 Recruiting 30 enrolled M.D. Anderson Cancer Center
RandomizedSingle-groupOpen-labelTreatment

Summary

This study investigates whether alteplase can help to improve pleural fluid drainage and dyspnea (breathlessness) in patients with non-draining malignant pleural effusion. Alteplase helps dissolve blood clots and is used to treat heart attacks, strokes, and clots in the lungs. Alteplase may help to control symptoms of breathlessness.

Timeline

Start
2023-08-17
Primary completion
2027-02-02
Completion
2027-02-02

Drugs

EvaluationDrugModalityDoseRoute
Subject Alteplase Protein / enzyme biologic Other